What do Rugby Weekend and The study of T-Cels have in common?
His name is Doctor Ian Orme… and he became involved in the field of Tuberculosis while training as a postdoctoral fellow at the Trudeau Institute from 1981 to 1986 and it turns out that not only is he a Professor of Microbiology, Immunology and Pathology AND An internationally known tuberculosis researcher, with more than 300 publications on the topic, but he also is a huge fan of Rugby…
(Audio) Dr Orme tells us about his roots in Saranac Lake and his interest in building rugby to what it is today by reducing the number of college teams, adding over 40 teams and including Lake Placid Fields to bring the numbers to 105 teams. He then talks about his work in Saranac Lake and compliments his partner Dr Andrea Cooper.
He’s talking about Dr. Andrea Cooper who worked with him at the Mycobacterial Research Labs atColoradoStateUniversityand began studying the protective immune response to Mycobacterium tuberculosis. Dr Cooper moved moved to the Trudeau Institute in January of 2002. This move allowed her to focus her investigation of the cellular immune response to Mycobacterium tuberculosis. Recent work has resulted in the definition of the roles of IL-12, IL-23 and IL-27 in both the primary and vaccine-induced immune response to this pathogen in the lung. Now before we really get started let’s sneak a peek at their relationship..
(Audio) Dr Orme tells us about how the two began their work – and gives us an overview of the history of their research
So we digressed a little bit to let Dr Orme Give you a bit of the history but we were talking about Doctor Andrea Cooper..
(Audio) Dr Orme tells us about Dr Cooper and jokes that he taught her how to write properly.
And it’s a good thing he taught her how to write because she has over 67 publications – including answers to questions like “What do we really know about how CD4 T cells control Mycobacterium tuberculosis?” and “The protective immune response to Mycobacterium tuberculosis.” To name just two of the 67..
Tuberculosis has long shapedSaranacLake’s identity, beginning with the pioneering medical and scientific work of Dr. Edward Livingston Trudeau and it continues today in the Trudeau Institute laboratory of Dr. Andrea Cooper. Much of the original spirit lives on in the John Black Room at the Saranac Laboratory, where Doctor Orme is about to begin his conversation about Tuberculosis as an epidemic in much of the world.
(Audio) Historic Saranac Lake’s Director Amy Catania introduces Dr Orme
And now to some of the specifics – Imagine for a moment, you’re a little cell or micro cell, ok maybe even smaller.. but as with everything in life, once and a while, something new in the strains of TB will be discovered and as Dr Orme will tell us regularly, some of these are very nasty indeed..
The topic for the evening is in fact “TB a Global Epidemic” and while the topic is a bit technical you can hear the excitement in his voice about the work they’re doing at Trudeau and atColoradoState..
Just one variable sounds simple enough – but it’s expensive, and requires a tremendous amount of thought – and in this case, Orme tells a story about why his lab needed a few better computers too..
If you missed it, we wished the two a happy anniversary during the birthday club.. But in all seriousness, this is a big deal in developing countries.. and in some areas drugs are in fact in human trials.. There is one – which was actually given a name which seems to have promise – for now though, we’ll call it 207 for short…
We’ll leave you with one thought.. and Not that’s it’s too technical.. but.. imagine as Doctor Orme proposes for a second.. The opportunity for this disease to spread into a major metropolitan area.. Sounds familiar doesn’t it… Oh and we forgot to mention that behind his facility at CSU, there’s a new gazillion dollar building whose sole purpose is to work on preventing just such an outbreak.. and as for the research, It’s inSaranac Lake,NY, at Trudeau Institute, and it’s atColoradoStateUniversity, whose roots stem from Doctor Ian Orme’s work at Trudeau inSaranacLake.. So we may not know as much about TB as we would like, but one thing is for sure..Rugbyweekend is just one of many contributing factors that’s helped prevent a worldwide epidemic.
Below; two links to listen to the entire one hour presenttion – each file is about 9mb and may take a few minutes to download;